صفحه محصول - پاورپوینت کم کاری تيروييد نوزادان

پاورپوینت کم کاری تيروييد نوزادان (pptx) 49 اسلاید

دسته بندی : پاورپوینت

نوع فایل : PowerPoint (.pptx) ( قابل ویرایش و آماده پرینت )

تعداد اسلاید: 49 اسلاید

قسمتی از متن PowerPoint (.pptx) :

کم کاری تيروييد نوزادان Causes of Congenital Hypothyroidism Developmental defects 1 every 4000 newborns; In Iran >1/1000 Complete absence of thyroid tissue Failure of thyroid to descend properly during embryologic development Route of descent (foramen caecum at the junction of anterior two thirds and posterior third of tongue to normal site or below) Biosynthetic defects in the thyroid Pituitary or hypothalamic failure Family with mutation in gene coding TSH β subunit Thyroid disorders and their approximate prevalence in the neonatal period Thyroid dysgenesis >1:1000-1:4000 Agenesis Hypogenesis Ectopia Thyroid dyshormonogenesis 1:40,000 Thyroid-stimulating hormone unresponsiveness Iodide trapping defect Organification defect Defect in thyroglobulin Iodotryrosine deiodinase deficiency Transient hypothyroidism 1:40,000 Drug induced Maternal antibody induced Idiopatic Hypothalamic-pituitary hypothyroidism 1:100,000 Hypothalamic-pituitary anomaly Panhypopituitarism Isolated thyroid-stimulating hormone deficiency Thyroid hormone resistance Differential diagnosis of transient congenital hypothyroidism Primary hypothyroidism Prenatal or postnatal iodine deficiency or excess Maternal antithyroid medication Maternal TSH receptor blocking antibodies Secondary or tertiary hypothyroidism Prenatal exposure to maternal hyperthyroidism Prematurity (particularly <27 weeks’ gestation) Drugs Steroids Dopamine Miscellaneous Isolated TSH elevation Low T4 with normal TSH Prematurity Undernutrition Low-T3 syndrome Importance of iodine inbrain development 50,000 brain cells produced/secondin developingfetal brain 100 billion brain cells in adult One million billion connections between these brain cells:Determine IQ Importance of iodine inbrain development 90 % of human brain development occurs between 3rd month of pregnancy & 3rd year of life(Critical period) Goiter has been known since the days of Lord Buddha and before Earliest evidence of goiter: 3000 BC Cretinism, Tip of the Iceberg World wide prevalence of goiter